Indirect Comparisons in Benefit Assessment
نویسندگان
چکیده
منابع مشابه
Indirect comparisons of therapeutic interventions
HEALTH POLITICAL BACKGROUND The comparison of the effectiveness of health technologies is not only laid down in German law (Social Code Book V, § 139 and § 35b) but also constitutes a central element of clinical guidelines and decision making in health care. Tools supporting decision making (e. g. Health Technology Assessments (HTA)) are therefore in need of a valid methodological repertoire fo...
متن کاملIndirect comparisons of competing interventions.
OBJECTIVES To survey the frequency of use of indirect comparisons in systematic reviews and evaluate the methods used in their analysis and interpretation. Also to identify alternative statistical approaches for the analysis of indirect comparisons, to assess the properties of different statistical methods used for performing indirect comparisons and to compare direct and indirect estimates of ...
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The debate about the effectiveness of investments in public infrastructure initiated by Aschauer suggests that there may be substantial discrepancies between the results of conventional cost-benefit analysis and the ultimate effects of such investments on welfare. This paper takes a closer look at this issue by investigating the existence of secondary or indirect effects under conditions of mon...
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Early benefit assessment in Germany under the legislative framework of AMNOG (Arzneimittelmarktneuordnungsgesetz) requires direct comparisons of the new drug with appropriate comparators determined by the Federal Joint Committee (G-BA). In case no head-to-head studies are available for direct comparisons, the submission of indirect comparisons is permitted to assess the additional benefit of th...
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We have entered an exciting new era of anticoagulation— with multiple new oral anticoagulants becoming available for use as potential replacements for warfarin, the vitamin K antagonist that has been the only oral agent available for 50 years! The most prominent of the indications for anticoagulation is for stroke prevention in patients with atrial fibrillation, where long-term, often life-long...
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ژورنال
عنوان ژورنال: Value in Health
سال: 2015
ISSN: 1098-3015
DOI: 10.1016/j.jval.2015.09.2734